2012年8月5日星期日
Non-specific symptoms and signs of IgA nephropathy
The study found that, IgA nephropathy and there is no specific symptoms or signs. So how to determine whether risk of IgA nephropathy?
IgA nephropathy is the most prominent clinical manifestations of recurrent gross hematuria, usually accompanied by proteinuria, but not necessarily. Sustained asymptomatic hematuria without proteinuria symptoms we call the isolated hematuria. Only a small number of patients with isolated hematuria symptoms. With many patients with glomerular nephropathy urine red blood cells, red blood cells in the urine of IgA nephropathy patients for the heterogeneity of red blood cells (compared with the normal red blood cell size and shape have change).
Often accompanied by symptoms of low-grade fever and low back pain due to repeated episodes of hematuria, this situation will often be misdiagnosed as a urinary tract infection or urinary stones. Using a microscope to carefully observe the Urine red blood cells, red blood cells showing non-uniformity of the glomerular lesions, strong glomerular lesions caused by the root cause of the hematuria symptoms.
However, the same symptoms may also occur in thin basement membrane nephropathy, hereditary nephritis and proliferative glomerulonephritis. By renal biopsy, immunofluorescence or electron microscopy easily separated with IgA nephropathy. In addition, proliferative glomerulonephritis also the symptoms of serum complement levels. The X chromosome inherited kidney disease, including hereditary nephritis (excluding from father to son type) deafness symptoms usually appear. By renal biopsy and electron microscopy of thin basement membrane nephropathy and IgA nephropathy easily separate areas.
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