Have to do with IgA nephropathy renal biopsy?

IgA nephropathy must do renal biopsy? IgA nephropathy is a kidney inherent features of immunoglobulin A deposition mainly caused by cell damage syndrome. Puncture needle into the kidney of the body, remove the small amount of kidney tissue for pathological analysis. There are two kinds of ways, First, the open puncture of the kidney biopsy method, first through the skin puncture renal biopsy in France, now mainly used the latter approach, many clinical genotyping method can not confirm the diagnosis, prognosis, etc., there are many using renal biopsy is useful in diagnosis, guide treatment, prognosis, and to investigate the clinical classification and pathological type of relationship, but also raise an important means of kidney disease clinical and research level. For in-depth study of the field and to explore the pathogenesis of kidney disease, and promote clinical and scientific research of kidney disease in depth, the development of kidney disease, has an important role.
Renal biopsy notes you know? Renal biopsy preoperative preparation? Someone to do before the renal biopsy was very worried, do not know whether they can adapt the renal biopsy, renal biopsy in the preoperative preparation should be noted that what impatience receive a kidney puncture, this practice is very strict taboo. Here's some Notes on renal biopsy.
Renal biopsy is an invasive examination, and choice of puncture cases not only need to master the adaptation levy, they also had to rule out contraindications.
⑴ absolute contraindications: ① significant bleeding tendency, ② severe hypertension, ③ mental illness or do not match operator, ④ solitary kidney, ⑤ small kidney.
⑵ relative contraindications: ① active pyelonephritis, renal tuberculosis, hydronephrosis, or empyema, renal abscess or renal abscess. ② renal tumor or renal artery aneurysm. ③ polycystic kidney disease or kidney large cysts. (4) kidney position is too high (deep breathing, kidney and the lower pole up to 12 ribs) or wandering kidney. The ⑤ chronic renal failure. The ⑥ obesity. ⑦ severe ascites. ⑧ heart failure, severe anemia, low blood volume, pregnant or elderly persons.
Before the renal puncture is well prepared is an important part in reducing complications. Preoperative should undertake the following tasks:
The ⑴ explain the necessity and safety of renal biopsy and possible complications to the patients and their families, and with the consent of the patients and their families agree. Explained to the patients with renal biopsy operation, the lifting of the patient's fear, in order to obtain the cooperation of the patient. Allowed to practice breath holding (renal biopsy will be temporarily hold your breath) and urinating in bed (bed 24 hours after renal biopsy) for close coordination.
⑵ tested positive, clotting time, platelet count and prothrombin time in order to understand whether the bleeding tendency.
⑶ check creatinine clearance, serum creatinine and blood urea nitrogen of kidney function, check the isotope renogram understanding of the sub-renal, and make a B super understanding of kidney size, location and activity.
(4) check the blood type, prepared blood, the skin of the preoperative routine cleaning kidney area.
⑸ surgery 2 to 3 days before the oral or intramuscular vitamin K
⑹ acute renal failure in patients with renal biopsy In addition to the laboratory prothrombin time, but also determination of the kaolin partial thromboplastin time, In addition to the check platelet count, should from time to time to check platelet function (aggregation, adhesion and release function), if abnormal, should be corrected before surgery. Abnormal platelet number and function can puncture the day before surgery, infusion of fresh platelets. Bleeding time cold precipitate correction of infusion rich clotting factor. Severe renal failure patients the best in the renal biopsy before the hemodialysis several times, 24 hours before the renal biopsy to stop dialysis, when the end of dialysis to protamine and heparin, and review of the clotting time of the test tube method, before the renal biopsy to confirm that the heparin The effect disappeared.
⑺ surgery the front of the empty bladder. Renal biopsy is usually divided into three categories: the the ⑴ through the skin puncture renal biopsy technique, the present study has been widely recognized and applied renal biopsy; ⑵ surgery to look directly into the open renal biopsy; ⑶ renal vein puncture renal biopsy surgery.
To sum up, the clinical significance of renal biopsy the following main points:
⑴ clear diagnosis: renal biopsy can make more than a third of patients with clinical diagnosis to be corrected.
(2) to guide treatment: nearly a third of patients with clinical treatment programs to be modified by renal biopsy.
⑶ prognosis: renal biopsy can more accurately evaluate the prognosis of patients with kidney disease.
In addition, sometimes in order to understand the effects of treatment or to understand the pathological progress (such as crescentic glomerulonephritis, lupus nephritis and IgA nephropathy, etc.) also need to be repeated kidney pathology.
Have to do with IgA nephropathy renal biopsy?
Different period of development of kidney disease pathological changes inconsistent. Same IgA nephropathy, pathological performance for almost all stages of development from a near-normal renal tissue to the majority of glomerular sclerosis. Therefore, to understand the morphological changes in kidney tissue clinicians to determine the condition, treatment of disease and prognosis and provides an important basis. It can be said that the kidney pathological examination of the development of nephrology in the development of a leap. At present, kidney pathology results has become the gold standard for diagnosis of kidney disease.