2012年8月5日星期日

How to diagnosis of IgA nephropathy


In the country of Japan, the law school-age children must receive routine urine examination. Therefore, children are often in the early IgA nephropathy will be checked out. In China only in the urine into the cola color or brown, people will note that the kidney problem.
There are many reasons that cause hematuria symptoms. Because many doctors are unfamiliar with IgA nephropathy, the patient may go through a series of urinary tests to determine if there is urinary tract infections or congenital malformations. But as long as the red blood cells in the urine under a microscope, you will find these red blood cells is no longer full and mellow, they look ragged edges, what seems to have been bitten by the same. This glomerulus has been damaged, but not yet confirmed what type of glomerulonephritis.
A doctor first thought may be glomerulonephritis caused by streptococcal infection, such symptoms of nephritis and IgA nephropathy, but with IgA nephropathy will heal this nephritis is usually the case. To rule out the possibility of post-streptococcal glomerulonephritis, patients need a variety of tests, including complete blood count and blood urea nitrogen, creatinine, Determination of anti-streptolysin blood.
Your doctor may also ask you to creatinine clearance test. Detected in the blood creatinine levels on the basis of the analysis in the urine of 24 hours to assess the level of kidney function, in order to determine the glomerular filtration rate. Creatinine is the end product of muscle metabolism, one of the most important functions in the kidney is cleared of creatinine in the blood. Creatinine clearance test does not help the doctor determine exactly what type of glomerulonephritis, but can determine the severity of inflammation and kidney damage. Kidney approximately every minute filtered five ounces of blood, IgA nephropathy in patients with glomerular filtration rate is decreased, which lead to glomerular capillary filtration area is reduced due to the inflammatory response, leading to the glomerular filtration rate reduced.
Proteinuria and hematuria, or other kidney disease, lack of features, such as azotemia or significant edema may be caused by IgA nephropathy, but only to the final diagnosis of renal biopsy.

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