IgA nephritis should do what?

1 urine test
(1) hematuria: about 40% to 45% of patients in the clinical performance of the naked eye or microscopic hematuria, from 35% to 40% of the patients showed simple microscopic hematuria or microscopic hematuria with a small amount of proteinuria. The sustainable gross hematuria few hours to a few days after to persistent microscopic hematuria, some patients with hematuria disappeared, but often seizures, reproduce gross hematuria attack.
(2) proteinuria: mild proteinuria, general urinary protein excretion <1g/24h, a small number of patients with massive proteinuria or even nephrotic syndrome.
2 immunological tests
(1) IgA increased: from about 1/4 to L / 2 of the patients serum IgA increased mainly multimeric IgA increased.
(2) circulating immune complexes: IgA circulating immune complexes and (or) IgG circulating immune complexes can be detected in the blood of about 1/5 to 2/3 of the children.
(3) anti-"O" elevated titer of anti-"O": A small number of patients.
(4) complement: C3, C4 and more normal.
3 renal biopsy: renal biopsy diagnosis of IgA nephropathy, the renal pathology light mirror change performance for mesangial degree from focal segmental proliferation to diffuse mesangial proliferative ranging. Part mesangial proliferative heavier visible The mesangial insert to form segmental two-track. Sometimes see segmental glomerulosclerosis, capillary collapse, balloon adhesions. Individual lesions severe hyaline change, global sclerosis, individual capillary tube loop necrosis and crescent formation. The Masson staining mesangial area a large number of addicted to the the fuchsin sediment renal immunopathological visible the mesangium significant IgA deposition. Electron microscope for varying degrees of mesangial cells and stromal hyperplasia, electron-dense material by mesangial area, Vice mesangial area extended to the endothelial cells of the capillary wall or on subcutaneous.